5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE
TL;DR: 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE (CAS 1005046-31-0) is a chemical compound with molecular formula C18H13Cl2F3N2O3 and molecular weight 432.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(4-chlorobenzoyl)-6-(4-chlorophenyl)-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one
Also Known As: 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE, 5-(4-chlorobenzoyl)-6-(4-chlorophenyl)-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one, 5-(4-chlorobenzoyl)-6-(4-chlorophenyl)-4-hydroxy-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one, 6-(4-chlorophenyl)-5-[(4-chlorophenyl)carbonyl]-4-hydroxy-4-(trifluoromethyl)- 1,3-diazaperhydroin-2-one, 6-(4-chlorophenyl)-5-[(4-chlorophenyl)carbonyl]-4-hydroxy-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
| Molecular Formula | C18H13Cl2F3N2O3 |
|---|---|
| Molecular Weight | 432.03 g/mol |
| LogP | 4.0973 |
| Topological Polar Surface Area | 78.43 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 432.02554 |
| Heavy Atoms | 28 |
| Complexity | 903.787 |
Chemical Identifiers
| CAS Number | 1005046-31-0 |
|---|---|
| SMILES | C1=CC(=CC=C1C2C(C(NC(=O)N2)(C(F)(F)F)O)C(=O)C3=CC=C(C=C3)Cl)Cl |
Product Overview
5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE (CAS 1005046-31-0), with molecular formula C18H13Cl2F3N2O3 and molecular weight 432.03 g/mol. IUPAC: 5-(4-chlorobenzoyl)-6-(4-chlorophenyl)-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one.
Chemical Property Profile of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE
Property Insights of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE
The XLogP value of 4.0973 indicates that 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.43 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE. Following Lipinski's Rule of Five, 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE?
The CAS number of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE is 1005046-31-0.
What is the molecular formula of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE?
The molecular formula of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE is C18H13Cl2F3N2O3.
What is the molecular weight of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE?
The molecular weight of 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE is 432.03 g/mol.
Where can I buy 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE?
You can request a quote for 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-CHLOROBENZOYL)-6-(4-CHLOROPHENYL)-4-HYDROXY-4-(TRIFLUOROMETHYL)TETRAHYDRO-2(1H)-PYRIMIDINONE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.