1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride
TL;DR: 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride (CAS 1003320-19-1) is a chemical compound with molecular formula C13H17ClN2O3 and molecular weight 284.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone;hydrochloride
Also Known As: Doxazosin EP Impurity B, 1-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride, 2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride, N- PiperazineHydrochloride, N-(1,4-Benzodioxan-2-Carbonyl)Piperazine Hydrochloride
| Molecular Formula | C13H17ClN2O3 |
|---|---|
| Molecular Weight | 284.09 g/mol |
| LogP | 0.68 |
| Topological Polar Surface Area | 50.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 284.09277 |
| Heavy Atoms | 19 |
| Complexity | 449.2694 |
Chemical Identifiers
| CAS Number | 1003320-19-1 |
|---|---|
| SMILES | C1CN(CCN1)C(=O)C2COC3=CC=CC=C3O2.Cl |
Product Overview
1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride (CAS 1003320-19-1), with molecular formula C13H17ClN2O3 and molecular weight 284.09 g/mol. IUPAC: 2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone;hydrochloride.
Chemical Property Profile of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride
Property Insights of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride
The XLogP value of 0.68 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride. With a topological polar surface area (TPSA) of 50.8 Ų, 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride?
The CAS number of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride is 1003320-19-1.
What is the molecular formula of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride?
The molecular formula of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride is C13H17ClN2O3.
What is the molecular weight of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride?
The molecular weight of 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride is 284.09 g/mol.
Where can I buy 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride?
You can request a quote for 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for 1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.