A0443/0020446
TL;DR: A0443/0020446 (CAS 1000374-22-0) is a chemical compound with molecular formula C23H19F2N3O and molecular weight 391.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8E)-2-amino-4-(4-fluorophenyl)-8-[(4-fluorophenyl)methylidene]-6-methyl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
Also Known As: A0443/0020446, 2-amino-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile, (8E)-2-amino-4-(4-fluorophenyl)-8-[(4-fluorophenyl)methylidene]-6-methyl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile, (8E)-2-amino-4-(4-fluorophenyl)-8-[(4-fluorophenyl)methylene]-6-methyl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile, (8E)-2-AMINO-4-(4-FLUOROPHENYL)-8-[(4-FLUOROPHENYL)METHYLIDENE]-6-METHYL-4H,5H,6H,7H,8H-PYRANO[3,2-C]PYRIDINE-3-CARBONITRILE
| Molecular Formula | C23H19F2N3O |
|---|---|
| Molecular Weight | 391.15 g/mol |
| LogP | 4.05558 |
| Topological Polar Surface Area | 62.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 391.14963 |
| Heavy Atoms | 29 |
| Complexity | 1076.6012 |
Chemical Identifiers
| CAS Number | 1000374-22-0 |
|---|---|
| SMILES | CN1C/C(=C\C2=CC=C(C=C2)F)/C3=C(C1)C(C(=C(O3)N)C#N)C4=CC=C(C=C4)F |
Product Overview
A0443/0020446 (CAS 1000374-22-0), with molecular formula C23H19F2N3O and molecular weight 391.15 g/mol. IUPAC: (8E)-2-amino-4-(4-fluorophenyl)-8-[(4-fluorophenyl)methylidene]-6-methyl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile.
Chemical Property Profile of A0443/0020446
Property Insights of A0443/0020446
The XLogP value of 4.05558 indicates that A0443/0020446 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.28 Ų falls within the moderate polarity range, balancing permeability and solubility for A0443/0020446. Following Lipinski's Rule of Five, A0443/0020446 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A0443/0020446?
The CAS number of A0443/0020446 is 1000374-22-0.
What is the molecular formula of A0443/0020446?
The molecular formula of A0443/0020446 is C23H19F2N3O.
What is the molecular weight of A0443/0020446?
The molecular weight of A0443/0020446 is 391.15 g/mol.
Where can I buy A0443/0020446?
You can request a quote for A0443/0020446 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A0443/0020446?
Yes, KEHONG BIO provides custom synthesis services for A0443/0020446 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.