2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile structure

2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile

TL;DR: 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile (CAS 99903-57-8) is a chemical compound with molecular formula C11H6ClF6N and molecular weight 301.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(4-chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile

Also Known As: 2-(4-chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile, Benzeneacetonitrile, 4-chloro-.alpha.-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]-

CAS: 99903-57-8
Molecular Formula C11H6ClF6N
Molecular Weight 301.01 g/mol
LogP 4.7
Topological Polar Surface Area 23.8 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 2
Exact Mass 301.0093
Heavy Atoms 19
Complexity 332.0

Chemical Identifiers

CAS Number 99903-57-8
SMILES C1=CC(=CC=C1C(C#N)C(C(F)(F)F)C(F)(F)F)Cl
InChIKey SKACAZKYCFBHSO-UHFFFAOYSA-N

Product Overview

2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile (CAS 99903-57-8), with molecular formula C11H6ClF6N and molecular weight 301.01 g/mol. IUPAC: 2-(4-chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile

XLogP
4.7
TPSA (Topological Polar Surface Area)
23.8
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
2
Heavy Atoms
19
Complexity
332.0
Exact Mass
301.0093
Monoisotopic Mass
301.0093
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile

The XLogP value of 4.7 indicates that 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.8 Ų, 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile?

The CAS number of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile is 99903-57-8.

What is the molecular formula of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile?

The molecular formula of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile is C11H6ClF6N.

What is the molecular weight of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile?

The molecular weight of 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile is 301.01 g/mol.

Where can I buy 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile?

You can request a quote for 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile?

Yes, KEHONG BIO provides custom synthesis services for 2-(4-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)butanenitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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