Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate structure

Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate

TL;DR: Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate (CAS 99903-44-3) is a chemical compound with molecular formula C13H18F6O4 and molecular weight 352.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

trans-ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate

Also Known As: Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate, Ethyl (1R,3S)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate, Cyclopropanecarboxylic acid, 3-(diethoxymethyl)-2,2-bis(trifluoromethyl)-, ethyl ester, trans-

CAS: 99903-44-3
Molecular Formula C13H18F6O4
Molecular Weight 352.11 g/mol
LogP 3.4
Topological Polar Surface Area 44.8 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 10
Rotatable Bonds 8
Exact Mass 352.11093
Heavy Atoms 23
Complexity 400.0

Chemical Identifiers

CAS Number 99903-44-3
SMILES CCOC([C@@H]1[C@H](C1(C(F)(F)F)C(F)(F)F)C(=O)OCC)OCC
InChIKey AOGSSUMXUIJOJD-YUMQZZPRSA-N

Product Overview

Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate (CAS 99903-44-3), with molecular formula C13H18F6O4 and molecular weight 352.11 g/mol. IUPAC: trans-ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate

XLogP
3.4
TPSA (Topological Polar Surface Area)
44.8
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
10
Rotatable Bonds
8
Heavy Atoms
23
Complexity
400.0
Exact Mass
352.11093
Monoisotopic Mass
352.11093
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate

The XLogP value of 3.4 indicates that Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.8 Ų, Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate has 0 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate?

The CAS number of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate is 99903-44-3.

What is the molecular formula of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate?

The molecular formula of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate is C13H18F6O4.

What is the molecular weight of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate?

The molecular weight of Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate is 352.11 g/mol.

Where can I buy Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate?

You can request a quote for Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl (1R,3R)-3-(diethoxymethyl)-2,2-bis(trifluoromethyl)cyclopropane-1-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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