8-Fluoronorfloxacin
TL;DR: 8-Fluoronorfloxacin (CAS 99726-76-8) is a chemical compound with molecular formula C16H17F2N3O3 and molecular weight 337.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-ethyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
Also Known As: 8-Fluoronorfloxacin, Lomefloxacin Impurity 2, Lomefloxacin Impurity 6, 3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-ethyl-4-oxo-7-(1-piperazinyl)-, 1-ethyl-6,8-difluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
| Molecular Formula | C16H17F2N3O3 |
|---|---|
| Molecular Weight | 337.12 g/mol |
| LogP | -1.1 |
| Topological Polar Surface Area | 72.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 3 |
| Exact Mass | 337.1238 |
| Heavy Atoms | 24 |
| Complexity | 551.0 |
Chemical Identifiers
| CAS Number | 99726-76-8 |
|---|---|
| SMILES | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNCC3)F)C(=O)O |
| InChIKey | YHRXPOLYCUTZAM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
8-Fluoronorfloxacin (CAS 99726-76-8), with molecular formula C16H17F2N3O3 and molecular weight 337.12 g/mol. IUPAC: 1-ethyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid.
Chemical Property Profile of 8-Fluoronorfloxacin
Property Insights of 8-Fluoronorfloxacin
The XLogP value of -1.1 indicates that 8-Fluoronorfloxacin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 72.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 8-Fluoronorfloxacin. Following Lipinski's Rule of Five, 8-Fluoronorfloxacin has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Fluoronorfloxacin?
The CAS number of 8-Fluoronorfloxacin is 99726-76-8.
What is the molecular formula of 8-Fluoronorfloxacin?
The molecular formula of 8-Fluoronorfloxacin is C16H17F2N3O3.
What is the molecular weight of 8-Fluoronorfloxacin?
The molecular weight of 8-Fluoronorfloxacin is 337.12 g/mol.
Where can I buy 8-Fluoronorfloxacin?
You can request a quote for 8-Fluoronorfloxacin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Fluoronorfloxacin?
Yes, KEHONG BIO provides custom synthesis services for 8-Fluoronorfloxacin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.