Naxagolide Hydrochloride
TL;DR: Naxagolide Hydrochloride (CAS 99705-65-4) is a chemical compound with molecular formula C15H22ClNO2 and molecular weight 283.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazin-9-ol;hydrochloride
Also Known As: NAXAGOLIDE HYDROCHLORIDE, Naxagolide HCl, dopazinol, ent Naxagolide Hydrochloride, Nazagolide HCl
| Molecular Formula | C15H22ClNO2 |
|---|---|
| Molecular Weight | 283.13 g/mol |
| LogP | 2.91 |
| Topological Polar Surface Area | 32.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 283.1339 |
| Heavy Atoms | 19 |
| Complexity | 284.0 |
Chemical Identifiers
| CAS Number | 99705-65-4 |
|---|---|
| SMILES | CCCN1CCO[C@H]2[C@H]1CCC3=C2C=C(C=C3)O.Cl |
| InChIKey | NNEACMQMRLNNIL-CTHHTMFSSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Naxagolide Hydrochloride (CAS 99705-65-4), with molecular formula C15H22ClNO2 and molecular weight 283.13 g/mol. IUPAC: (4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazin-9-ol;hydrochloride.
Chemical Property Profile of Naxagolide Hydrochloride
Property Insights of Naxagolide Hydrochloride
The XLogP value of 2.91 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Naxagolide Hydrochloride. With a topological polar surface area (TPSA) of 32.7 Ų, Naxagolide Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Naxagolide Hydrochloride has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naxagolide Hydrochloride?
The CAS number of Naxagolide Hydrochloride is 99705-65-4.
What is the molecular formula of Naxagolide Hydrochloride?
The molecular formula of Naxagolide Hydrochloride is C15H22ClNO2.
What is the molecular weight of Naxagolide Hydrochloride?
The molecular weight of Naxagolide Hydrochloride is 283.13 g/mol.
Where can I buy Naxagolide Hydrochloride?
You can request a quote for Naxagolide Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naxagolide Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Naxagolide Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.