Piclamilast
TL;DR: Piclamilast (CAS 99513-01-6) is a chemical compound with molecular formula C18H18Cl2N2O3 and molecular weight 380.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-cyclopentyloxy-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide
Also Known As: Piclamilast, Cpodpmb, piclamilastum, Piclamilast [INN], 1xon
| Molecular Formula | C18H18Cl2N2O3 |
|---|---|
| Molecular Weight | 380.07 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 60.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 380.06946 |
| Heavy Atoms | 25 |
| Complexity | 438.0 |
Chemical Identifiers
| CAS Number | 99513-01-6 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3 |
| InChIKey | RRRUXBQSQLKHEL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Piclamilast (CAS 99513-01-6), with molecular formula C18H18Cl2N2O3 and molecular weight 380.07 g/mol. IUPAC: 3-cyclopentyloxy-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide.
Chemical Property Profile of Piclamilast
Property Insights of Piclamilast
The XLogP value of 4.2 indicates that Piclamilast is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Piclamilast. Following Lipinski's Rule of Five, Piclamilast has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Piclamilast?
The CAS number of Piclamilast is 99513-01-6.
What is the molecular formula of Piclamilast?
The molecular formula of Piclamilast is C18H18Cl2N2O3.
What is the molecular weight of Piclamilast?
The molecular weight of Piclamilast is 380.07 g/mol.
Where can I buy Piclamilast?
You can request a quote for Piclamilast directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Piclamilast?
Yes, KEHONG BIO provides custom synthesis services for Piclamilast and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.