N-Crotonyldeacetylcolchicine
TL;DR: N-Crotonyldeacetylcolchicine (CAS 99481-33-1) is a chemical compound with molecular formula C24H27NO6 and molecular weight 425.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)but-2-enamide
Also Known As: N-Crotonyldeacetylcolchicine, (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-2-butenamide, 2-Butenamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, (E)-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)but-2-enamide, RefChem:1091685
| Molecular Formula | C24H27NO6 |
|---|---|
| Molecular Weight | 425.18 g/mol |
| LogP | 3.4278 |
| Topological Polar Surface Area | 83.09 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 425.18384 |
| Heavy Atoms | 31 |
| Complexity | 1076.4454 |
Chemical Identifiers
| CAS Number | 99481-33-1 |
|---|---|
| SMILES | C/C=C/C(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
Product Overview
N-Crotonyldeacetylcolchicine (CAS 99481-33-1), with molecular formula C24H27NO6 and molecular weight 425.18 g/mol. IUPAC: (E)-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)but-2-enamide.
Chemical Property Profile of N-Crotonyldeacetylcolchicine
Property Insights of N-Crotonyldeacetylcolchicine
The XLogP value of 3.4278 indicates that N-Crotonyldeacetylcolchicine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.09 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Crotonyldeacetylcolchicine. Following Lipinski's Rule of Five, N-Crotonyldeacetylcolchicine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Crotonyldeacetylcolchicine?
The CAS number of N-Crotonyldeacetylcolchicine is 99481-33-1.
What is the molecular formula of N-Crotonyldeacetylcolchicine?
The molecular formula of N-Crotonyldeacetylcolchicine is C24H27NO6.
What is the molecular weight of N-Crotonyldeacetylcolchicine?
The molecular weight of N-Crotonyldeacetylcolchicine is 425.18 g/mol.
Where can I buy N-Crotonyldeacetylcolchicine?
You can request a quote for N-Crotonyldeacetylcolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Crotonyldeacetylcolchicine?
Yes, KEHONG BIO provides custom synthesis services for N-Crotonyldeacetylcolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.