N-Acryloyldeacetylcolchicine
TL;DR: N-Acryloyldeacetylcolchicine (CAS 99481-32-0) is a chemical compound with molecular formula C23H25NO6 and molecular weight 411.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]prop-2-enamide
Also Known As: N-Acryloyldeacetylcolchicine, (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-2-propenamide, 2-Propenamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, 2-Propenamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalene-7-yl)-, (S)-, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]prop-2-enamide
| Molecular Formula | C23H25NO6 |
|---|---|
| Molecular Weight | 411.17 g/mol |
| LogP | 3.0377 |
| Topological Polar Surface Area | 83.09 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 411.16818 |
| Heavy Atoms | 30 |
| Complexity | 1046.6525 |
Chemical Identifiers
| CAS Number | 99481-32-0 |
|---|---|
| SMILES | COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C=C |
Product Overview
N-Acryloyldeacetylcolchicine (CAS 99481-32-0), with molecular formula C23H25NO6 and molecular weight 411.17 g/mol. IUPAC: N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]prop-2-enamide.
Chemical Property Profile of N-Acryloyldeacetylcolchicine
Property Insights of N-Acryloyldeacetylcolchicine
The XLogP value of 3.0377 indicates that N-Acryloyldeacetylcolchicine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.09 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Acryloyldeacetylcolchicine. Following Lipinski's Rule of Five, N-Acryloyldeacetylcolchicine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Acryloyldeacetylcolchicine?
The CAS number of N-Acryloyldeacetylcolchicine is 99481-32-0.
What is the molecular formula of N-Acryloyldeacetylcolchicine?
The molecular formula of N-Acryloyldeacetylcolchicine is C23H25NO6.
What is the molecular weight of N-Acryloyldeacetylcolchicine?
The molecular weight of N-Acryloyldeacetylcolchicine is 411.17 g/mol.
Where can I buy N-Acryloyldeacetylcolchicine?
You can request a quote for N-Acryloyldeacetylcolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Acryloyldeacetylcolchicine?
Yes, KEHONG BIO provides custom synthesis services for N-Acryloyldeacetylcolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.