Hoe 288
TL;DR: Hoe 288 (CAS 99146-53-9) is a chemical compound with molecular formula C27H38N2O5 and molecular weight 470.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1'-[2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl]spiro[bicyclo[2.2.2]octane-2,4'-pyrrolidine]-2'-carboxylic acid
Also Known As: Hoe 288, (3'S-(1'(R*(R*)),3'alpha,5'beta))-1'-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)spiro(bicyclo(2.2.2)octane-2,3'-pyrrolidine)-5'-carboxylic acid, 1'-[2-[(1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl]spiro[bicyclo[2.2.2]octane-2,4'-pyrrolidine]-2'-carboxylic acid, 1'-{2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl}spiro[bicyclo[2.2.2]octane-2,3'-pyrrolidine]-5'-carboxylic acid(non-preferred name), Spiro(bicyclo(2.2.2)octane-2,3'-pyrrolidine)-5'-carboxylic acid, 1'-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, (3'S-(1'(R*(R*)),3'alpha,5'beta))-
| Molecular Formula | C27H38N2O5 |
|---|---|
| Molecular Weight | 470.28 g/mol |
| LogP | 2.3 |
| Topological Polar Surface Area | 95.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 10 |
| Exact Mass | 470.27808 |
| Heavy Atoms | 34 |
| Complexity | 743.0 |
Chemical Identifiers
| CAS Number | 99146-53-9 |
|---|---|
| SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3(CC4CCC3CC4)CC2C(=O)O |
| InChIKey | NWHCDUODNHUNLN-UHFFFAOYSA-N |
Product Overview
Hoe 288 (CAS 99146-53-9), with molecular formula C27H38N2O5 and molecular weight 470.28 g/mol. IUPAC: 1'-[2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl]spiro[bicyclo[2.2.2]octane-2,4'-pyrrolidine]-2'-carboxylic acid.
Chemical Property Profile of Hoe 288
Property Insights of Hoe 288
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Hoe 288. The TPSA of 95.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Hoe 288. Following Lipinski's Rule of Five, Hoe 288 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hoe 288?
The CAS number of Hoe 288 is 99146-53-9.
What is the molecular formula of Hoe 288?
The molecular formula of Hoe 288 is C27H38N2O5.
What is the molecular weight of Hoe 288?
The molecular weight of Hoe 288 is 470.28 g/mol.
Where can I buy Hoe 288?
You can request a quote for Hoe 288 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hoe 288?
Yes, KEHONG BIO provides custom synthesis services for Hoe 288 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.