Drotaverin hydrochloride structure

Drotaverin hydrochloride

TL;DR: Drotaverin hydrochloride (CAS 985-12-6) is a chemical compound with molecular formula C24H32ClNO4 and molecular weight 433.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-3,4-dihydro-2H-isoquinoline;hydrochloride

Also Known As: drotaverine, DROTAVERINE HYDROCHLORIDE, Drotin, Tetraspasmin-Lefa, Drotaverin HCl

CAS: 985-12-6
Molecular Formula C24H32ClNO4
Molecular Weight 433.20 g/mol
LogP 5.35
Topological Polar Surface Area 49.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 9
Exact Mass 433.202
Heavy Atoms 30
Complexity 511.0

Chemical Identifiers

CAS Number 985-12-6
SMILES CCOC1=C(C=C(C=C1)C=C2C3=CC(=C(C=C3CCN2)OCC)OCC)OCC.Cl
InChIKey JBFLYOLJRKJYNV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (51 patents)

Product Overview

Drotaverin hydrochloride (CAS 985-12-6), with molecular formula C24H32ClNO4 and molecular weight 433.20 g/mol. IUPAC: 1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-3,4-dihydro-2H-isoquinoline;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Drotaverin hydrochloride

XLogP
5.35
TPSA (Topological Polar Surface Area)
49.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
9
Heavy Atoms
30
Complexity
511.0
Exact Mass
433.202
Monoisotopic Mass
433.202
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Drotaverin hydrochloride

The XLogP value of 5.35 indicates that Drotaverin hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.0 Ų, Drotaverin hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Drotaverin hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Drotaverin hydrochloride?

The CAS number of Drotaverin hydrochloride is 985-12-6.

What is the molecular formula of Drotaverin hydrochloride?

The molecular formula of Drotaverin hydrochloride is C24H32ClNO4.

What is the molecular weight of Drotaverin hydrochloride?

The molecular weight of Drotaverin hydrochloride is 433.20 g/mol.

Where can I buy Drotaverin hydrochloride?

You can request a quote for Drotaverin hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Drotaverin hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Drotaverin hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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