7-Hydroxy Aminopterin
TL;DR: 7-Hydroxy Aminopterin (CAS 97772-99-1) is a chemical compound with molecular formula C19H20N8O6 and molecular weight 456.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[4-[(2,4-diamino-7-oxo-8H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
Also Known As: 7-Hydroxy Aminopterin, 2-[[4-[(2,4-diamino-7-oxo-8H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic Acid, L-Glutamic acid,N-[4-[[(2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]-, N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; N-[p-[[(2,4-Diamino-7-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; N-[4-[[(2,4-Diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]- L-Glutamic Acid;
| Molecular Formula | C19H20N8O6 |
|---|---|
| Molecular Weight | 456.15 g/mol |
| LogP | -0.4626 |
| Topological Polar Surface Area | 239.3 Ų |
| Hydrogen Bond Donors | 7 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Exact Mass | 456.15057 |
| Heavy Atoms | 33 |
| Complexity | 1273.7533 |
Chemical Identifiers
| CAS Number | 97772-99-1 |
|---|---|
| SMILES | C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=NC3=C(N=C(N=C3NC2=O)N)N |
Product Overview
7-Hydroxy Aminopterin (CAS 97772-99-1), with molecular formula C19H20N8O6 and molecular weight 456.15 g/mol. IUPAC: 2-[[4-[(2,4-diamino-7-oxo-8H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid.
Chemical Property Profile of 7-Hydroxy Aminopterin
Property Insights of 7-Hydroxy Aminopterin
The XLogP value of -0.4626 indicates that 7-Hydroxy Aminopterin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 239.3 Ų indicates high polarity, suggesting 7-Hydroxy Aminopterin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 7-Hydroxy Aminopterin has 7 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Hydroxy Aminopterin?
The CAS number of 7-Hydroxy Aminopterin is 97772-99-1.
What is the molecular formula of 7-Hydroxy Aminopterin?
The molecular formula of 7-Hydroxy Aminopterin is C19H20N8O6.
What is the molecular weight of 7-Hydroxy Aminopterin?
The molecular weight of 7-Hydroxy Aminopterin is 456.15 g/mol.
Where can I buy 7-Hydroxy Aminopterin?
You can request a quote for 7-Hydroxy Aminopterin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Hydroxy Aminopterin?
Yes, KEHONG BIO provides custom synthesis services for 7-Hydroxy Aminopterin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.