1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
TL;DR: 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol (CAS 96719-63-0) is a chemical compound with molecular formula C21H18FNO and molecular weight 319.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluorophenyl)-2-phenyl-3,4-dihydro-1H-isoquinolin-6-ol
Also Known As: Estrogen receptor modulator 11, tetrahydroisoquinoline derivative, 27, 1-(4-fluorophenyl)-2-phenyl-3,4-dihydro-1H-isoquinolin-6-ol, 1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
| Molecular Formula | C21H18FNO |
|---|---|
| Molecular Weight | 319.14 g/mol |
| LogP | 4.6834 |
| Topological Polar Surface Area | 23.47 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 319.13724 |
| Heavy Atoms | 24 |
| Complexity | 845.47253 |
Chemical Identifiers
| CAS Number | 96719-63-0 |
|---|---|
| SMILES | C1CN(C(C2=C1C=C(C=C2)O)C3=CC=C(C=C3)F)C4=CC=CC=C4 |
Product Overview
1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol (CAS 96719-63-0), with molecular formula C21H18FNO and molecular weight 319.14 g/mol. IUPAC: 1-(4-fluorophenyl)-2-phenyl-3,4-dihydro-1H-isoquinolin-6-ol.
Chemical Property Profile of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
Property Insights of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
The XLogP value of 4.6834 indicates that 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.47 Ų, 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol?
The CAS number of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol is 96719-63-0.
What is the molecular formula of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol?
The molecular formula of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol is C21H18FNO.
What is the molecular weight of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol?
The molecular weight of 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol is 319.14 g/mol.
Where can I buy 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol?
You can request a quote for 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-Fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.