NCI60_004450 structure

NCI60_004450

TL;DR: NCI60_004450 (CAS 96699-71-7) is a chemical compound with molecular formula C22H25ClN2OS and molecular weight 400.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

8-[3-(2-chlorophenothiazin-10-yl)propyl]-8-azabicyclo[3.2.1]octan-3-ol

Also Known As: NCI60_004450, 8-[3-(2-chloro-10h-phenothiazin-10-yl)propyl]-8-azabicyclo[3.2.1]octan-3-ol, J2.291.983K, 8-(3-(10-(2-Chlorophenothiazinyl))propyl)pseudo-3-hydroxynortropane, 1-alpha-H,5-alpha-H-Nortropan-3-beta-ol, 8-(3-(2-chlorophenothiazin-10-yl)propyl)-

CAS: 96699-71-7
Molecular Formula C22H25ClN2OS
Molecular Weight 400.14 g/mol
LogP 5.7
Topological Polar Surface Area 52.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 400.1376
Heavy Atoms 27
Complexity 509.0

Chemical Identifiers

CAS Number 96699-71-7
SMILES C1CC2CC(CC1N2CCCN3C4=CC=CC=C4SC5=C3C=C(C=C5)Cl)O
InChIKey FVXMKGRYMOKOFX-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

NCI60_004450 (CAS 96699-71-7), with molecular formula C22H25ClN2OS and molecular weight 400.14 g/mol. IUPAC: 8-[3-(2-chlorophenothiazin-10-yl)propyl]-8-azabicyclo[3.2.1]octan-3-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NCI60_004450

XLogP
5.7
TPSA (Topological Polar Surface Area)
52.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
27
Complexity
509.0
Exact Mass
400.1376
Monoisotopic Mass
400.1376
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NCI60_004450

The XLogP value of 5.7 indicates that NCI60_004450 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.0 Ų, NCI60_004450 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, NCI60_004450 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NCI60_004450?

The CAS number of NCI60_004450 is 96699-71-7.

What is the molecular formula of NCI60_004450?

The molecular formula of NCI60_004450 is C22H25ClN2OS.

What is the molecular weight of NCI60_004450?

The molecular weight of NCI60_004450 is 400.14 g/mol.

Where can I buy NCI60_004450?

You can request a quote for NCI60_004450 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NCI60_004450?

Yes, KEHONG BIO provides custom synthesis services for NCI60_004450 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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