Pyroglutamyl-histidyl-prolyl-2-naphthylamide
TL;DR: Pyroglutamyl-histidyl-prolyl-2-naphthylamide (CAS 96583-49-2) is a chemical compound with molecular formula C26H28N6O4 and molecular weight 488.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-3-(4H-imidazol-4-yl)-1-[[(2S)-1-naphthalen-2-ylpyrrolidine-2-carbonyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pglu-his-pro-2NA, TRH-BetaNA, TRH-, ANA, PYR-HIS-PRO-BETANA
| Molecular Formula | C26H28N6O4 |
|---|---|
| Molecular Weight | 488.22 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 132.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 488.2172 |
| Heavy Atoms | 36 |
| Complexity | 935.0 |
Chemical Identifiers
| CAS Number | 96583-49-2 |
|---|---|
| SMILES | C1C[C@H](N(C1)C2=CC3=CC=CC=C3C=C2)C(=O)NC(=O)[C@H](CC4C=NC=N4)NC(=O)[C@@H]5CCC(=O)N5 |
| InChIKey | VHPCPKIDRHHIHE-WDHNVLQZSA-N |
Product Overview
Pyroglutamyl-histidyl-prolyl-2-naphthylamide (CAS 96583-49-2), with molecular formula C26H28N6O4 and molecular weight 488.22 g/mol. IUPAC: (2S)-N-[(2S)-3-(4H-imidazol-4-yl)-1-[[(2S)-1-naphthalen-2-ylpyrrolidine-2-carbonyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Pyroglutamyl-histidyl-prolyl-2-naphthylamide
Property Insights of Pyroglutamyl-histidyl-prolyl-2-naphthylamide
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Pyroglutamyl-histidyl-prolyl-2-naphthylamide. The TPSA of 132.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Pyroglutamyl-histidyl-prolyl-2-naphthylamide. Following Lipinski's Rule of Five, Pyroglutamyl-histidyl-prolyl-2-naphthylamide has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-histidyl-prolyl-2-naphthylamide?
The CAS number of Pyroglutamyl-histidyl-prolyl-2-naphthylamide is 96583-49-2.
What is the molecular formula of Pyroglutamyl-histidyl-prolyl-2-naphthylamide?
The molecular formula of Pyroglutamyl-histidyl-prolyl-2-naphthylamide is C26H28N6O4.
What is the molecular weight of Pyroglutamyl-histidyl-prolyl-2-naphthylamide?
The molecular weight of Pyroglutamyl-histidyl-prolyl-2-naphthylamide is 488.22 g/mol.
Where can I buy Pyroglutamyl-histidyl-prolyl-2-naphthylamide?
You can request a quote for Pyroglutamyl-histidyl-prolyl-2-naphthylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-histidyl-prolyl-2-naphthylamide?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-histidyl-prolyl-2-naphthylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.