Nih 10367 structure

Nih 10367

TL;DR: Nih 10367 (CAS 96453-67-7) is a chemical compound with molecular formula C21H25NO6 and molecular weight 387.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl (2'R,4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methylspiro[2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,3'-oxirane]-2'-carboxylate

Also Known As: Nih 10367, Ethyl 4,5-epoxy-3,14-dihydroxy-17-methylspiro(morphinan-6,2'-oxirane)-3'-carboxylate (3'R,5alpha,6beta)-, Ethyl (2'R,4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methylspiro[2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,3'-oxirane]-2'-carboxylate, Ethyl (3'R,4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H,7aH-spiro[4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,2'-oxirane]-3'-carboxylate, Ethyl 4a,9-dihydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H,7aH-spiro[4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,2'-oxirane]-3'-carboxylate

CAS: 96453-67-7
Molecular Formula C21H25NO6
Molecular Weight 387.17 g/mol
LogP 0.8768
Topological Polar Surface Area 91.76 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 2
Exact Mass 387.16818
Heavy Atoms 28
Complexity 903.12714

Chemical Identifiers

CAS Number 96453-67-7
SMILES CCOC(=O)[C@H]1C2(O1)CC[C@]3([C@H]4CC5=C6[C@]3([C@H]2OC6=C(C=C5)O)CCN4C)O

Product Overview

Nih 10367 (CAS 96453-67-7), with molecular formula C21H25NO6 and molecular weight 387.17 g/mol. IUPAC: ethyl (2'R,4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methylspiro[2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,3'-oxirane]-2'-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Nih 10367

XLogP
0.8768
TPSA (Topological Polar Surface Area)
91.76
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
2
Heavy Atoms
28
Complexity
903.12714
Exact Mass
387.16818
Monoisotopic Mass
387.16818
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nih 10367

The XLogP value of 0.8768 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nih 10367. The TPSA of 91.76 Ų falls within the moderate polarity range, balancing permeability and solubility for Nih 10367. Following Lipinski's Rule of Five, Nih 10367 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nih 10367?

The CAS number of Nih 10367 is 96453-67-7.

What is the molecular formula of Nih 10367?

The molecular formula of Nih 10367 is C21H25NO6.

What is the molecular weight of Nih 10367?

The molecular weight of Nih 10367 is 387.17 g/mol.

Where can I buy Nih 10367?

You can request a quote for Nih 10367 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nih 10367?

Yes, KEHONG BIO provides custom synthesis services for Nih 10367 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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