Dehydrofelodipine
TL;DR: Dehydrofelodipine (CAS 96382-71-7) is a chemical compound with molecular formula C18H17Cl2NO4 and molecular weight 381.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-O-ethyl 5-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
Also Known As: Dehydrofelodipine, Dehydro Felodipine, felodipine, Felodipine EP Impurity A, Felodipine M (dehydro)
| Molecular Formula | C18H17Cl2NO4 |
|---|---|
| Molecular Weight | 381.05 g/mol |
| LogP | 4.6 |
| Topological Polar Surface Area | 65.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 381.05347 |
| Heavy Atoms | 25 |
| Complexity | 490.0 |
Chemical Identifiers
| CAS Number | 96382-71-7 |
|---|---|
| SMILES | CCOC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl |
| InChIKey | REQRUBNOOIAHMG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Dehydrofelodipine (CAS 96382-71-7), with molecular formula C18H17Cl2NO4 and molecular weight 381.05 g/mol. IUPAC: 3-O-ethyl 5-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate.
Chemical Property Profile of Dehydrofelodipine
Property Insights of Dehydrofelodipine
The XLogP value of 4.6 indicates that Dehydrofelodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Dehydrofelodipine. Following Lipinski's Rule of Five, Dehydrofelodipine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dehydrofelodipine?
The CAS number of Dehydrofelodipine is 96382-71-7.
What is the molecular formula of Dehydrofelodipine?
The molecular formula of Dehydrofelodipine is C18H17Cl2NO4.
What is the molecular weight of Dehydrofelodipine?
The molecular weight of Dehydrofelodipine is 381.05 g/mol.
Where can I buy Dehydrofelodipine?
You can request a quote for Dehydrofelodipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dehydrofelodipine?
Yes, KEHONG BIO provides custom synthesis services for Dehydrofelodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.