Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-
TL;DR: Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- (CAS 959042-70-7) is a chemical compound with molecular formula C7H4Cl2N2S2 and molecular weight 249.92 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4,5-dichlorothiophen-2-yl)-1,3-thiazol-2-amine
Also Known As: Avatrombopag Impurity 26, Avatrombopag Impurity 29, Avatrombopag Impurity 33, 4-(4,5-Dichlorothiophen-2-yl)thiazol-2-amine, Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-
| Molecular Formula | C7H4Cl2N2S2 |
|---|---|
| Molecular Weight | 249.92 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 95.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 249.9193 |
| Heavy Atoms | 13 |
| Complexity | 195.0 |
Chemical Identifiers
| CAS Number | 959042-70-7 |
|---|---|
| SMILES | C1=C(SC(=C1Cl)Cl)C2=CSC(=N2)N |
| InChIKey | IGRUEOVREZXPII-UHFFFAOYSA-N |
Product Overview
Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- (CAS 959042-70-7), with molecular formula C7H4Cl2N2S2 and molecular weight 249.92 g/mol. IUPAC: 4-(4,5-dichlorothiophen-2-yl)-1,3-thiazol-2-amine.
Chemical Property Profile of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-
Property Insights of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-
The XLogP value of 3.6 indicates that Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-. Following Lipinski's Rule of Five, Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-?
The CAS number of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- is 959042-70-7.
What is the molecular formula of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-?
The molecular formula of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- is C7H4Cl2N2S2.
What is the molecular weight of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-?
The molecular weight of Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- is 249.92 g/mol.
Where can I buy Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-?
You can request a quote for Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-?
Yes, KEHONG BIO provides custom synthesis services for Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.