![(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide structure](/static/products/958/958955-90-3.png)
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide
概要：(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide（CAS 958955-90-3）是一种化学化合物，分子式为C22H17FN4O3，分子量为404.13 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(1R,2S,6R,7S)-4-(4-fluorophenyl)-3,5-dioxo-N-phenyl-4,8,9-triazatricyclo[6.4.0.02,6]dodeca-9,11-diene-7-carboxamide
又称：(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide, (1R,2S,6R,7S)-4-(4-fluorophenyl)-3,5-dioxo-N-phenyl-4,8,9-triazatricyclo[6.4.0.02,6]dodeca-9,11-diene-7-carboxamide, (4aR,4bS,7aR,8S)-6-(4-Fluoro-phenyl)-5,7-dioxo-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3'4':3,4]pyrrolo[ 1,2-b]pyridazine-8-carboxylic acid phenylamide
| 分子式 | C22H17FN4O3 |
|---|---|
| 分子量 | 404.13 g/mol |
| LogP | 2.1784 |
| 拓扑极性表面积 | 82.08 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 5 |
| 可旋转键数 | 3 |
| 精确质量 | 404.12848 |
| 重原子数 | 30 |
| 复杂度 | 1083.3213 |
化学标识符
| CAS 编号 | 958955-90-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)NC(=O)[C@@H]2[C@H]3[C@@H]([C@@H]4N2N=CC=C4)C(=O)N(C3=O)C5=CC=C(C=C5)F |
产品概述
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide（CAS 958955-90-3），分子式为C22H17FN4O3，分子量为404.13 g/mol。IUPAC名：(1R,2S,6R,7S)-4-(4-fluorophenyl)-3,5-dioxo-N-phenyl-4,8,9-triazatricyclo[6.4.0.02,6]dodeca-9,11-diene-7-carboxamide。
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide化学性质概览
属性洞察：(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的XLogP值为2.1784，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为82.08 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide有1个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的CAS号是多少？
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的CAS号为958955-90-3。
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的分子式是什么？
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的分子式为C22H17FN4O3。
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的分子量是多少？
(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的分子量为404.13 g/mol。
在哪里可以购买(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide？
您可以直接向科弘生物询价(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide的定制合成服务？
是的，科弘生物提供(4aR,4bS,7aR,8S)-6-(4-fluorophenyl)-5,7-dioxo-N-phenyl-4b,5,6,7,7a,8-hexahydro-4aH-pyrrolo[3',4':3,4]pyrrolo[1,2-b]pyridazine-8-carboxamide及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。