![(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione structure](/static/products/958/958938-19-7.png)
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione
概要：(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione（CAS 958938-19-7）是一种化学化合物，分子式为C26H20FN3O4，分子量为457.14 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(1S,3R,3aR,6aS)-5-(4-fluorophenyl)-1-[(4-hydroxyphenyl)methyl]spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione
又称：(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione, (1S,3R,3aR,6aS)-5-(4-fluorophenyl)-1-[(4-hydroxyphenyl)methyl]spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione, Opera_ID_1824
| 分子式 | C26H20FN3O4 |
|---|---|
| 分子量 | 457.14 g/mol |
| LogP | 2.699 |
| 拓扑极性表面积 | 98.74 Ų |
| 氢键供体数 | 3 |
| 氢键受体数 | 5 |
| 可旋转键数 | 3 |
| 精确质量 | 457.1438 |
| 重原子数 | 34 |
| 复杂度 | 1340.9115 |
化学标识符
| CAS 编号 | 958938-19-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)[C@]3([C@H]4[C@@H]([C@@H](N3)CC5=CC=C(C=C5)O)C(=O)N(C4=O)C6=CC=C(C=C6)F)C(=O)N2 |
产品概述
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione（CAS 958938-19-7），分子式为C26H20FN3O4，分子量为457.14 g/mol。IUPAC名：(1S,3R,3aR,6aS)-5-(4-fluorophenyl)-1-[(4-hydroxyphenyl)methyl]spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione。
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione化学性质概览
属性洞察：(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的XLogP值为2.699，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为98.74 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione有3个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的CAS号是多少？
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的CAS号为958938-19-7。
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子式是什么？
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子式为C26H20FN3O4。
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子量是多少？
(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子量为457.14 g/mol。
在哪里可以购买(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione？
您可以直接向科弘生物询价(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的定制合成服务？
是的，科弘生物提供(1'R,3'S,3a'S,6a'R)-5'-(4-fluorophenyl)-3'-(4-hydroxybenzyl)-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。