![(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione structure](/static/products/958/958845-88-0.png)
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione
概要：(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione（CAS 958845-88-0）是一种化学化合物，分子式为C26H20FN3O4，分子量为457.14 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(3aR,6aS)-5'-fluoro-1-[(4-hydroxyphenyl)methyl]-5-phenylspiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione
又称：(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione, (3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3a',6a'-dihydro-2'H-spiro[indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(1H,3'H,5'H)-trione, (3aR,6aS)-5'-fluoro-1-[(4-hydroxyphenyl)methyl]-5-phenylspiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione
| 分子式 | C26H20FN3O4 |
|---|---|
| 分子量 | 457.14 g/mol |
| LogP | 2.4 |
| 拓扑极性表面积 | 98.7 Ų |
| 氢键供体数 | 3 |
| 氢键受体数 | 6 |
| 可旋转键数 | 3 |
| 精确质量 | 457.1438 |
| 重原子数 | 34 |
| 复杂度 | 855.0 |
化学标识符
| CAS 编号 | 958845-88-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C(=O)[C@H]3[C@@H](C2=O)C4(C5=C(C=CC(=C5)F)NC4=O)NC3CC6=CC=C(C=C6)O |
| InChIKey | HDMHJKBCBGGPAR-YPHDTHBOSA-N |
产品概述
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione（CAS 958845-88-0），分子式为C26H20FN3O4，分子量为457.14 g/mol。IUPAC名：(3aR,6aS)-5'-fluoro-1-[(4-hydroxyphenyl)methyl]-5-phenylspiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-2',4,6-trione。
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione化学性质概览
属性洞察：(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的XLogP值为2.4，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为98.7 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione有3个氢键供体和6个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的CAS号是多少？
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的CAS号为958845-88-0。
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子式是什么？
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子式为C26H20FN3O4。
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子量是多少？
(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的分子量为457.14 g/mol。
在哪里可以购买(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione？
您可以直接向科弘生物询价(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione的定制合成服务？
是的，科弘生物提供(3a'S,6a'R)-5-fluoro-3'-(4-hydroxybenzyl)-5'-phenyl-3',3a'-dihydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(5'H,6a'H)-trione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。