5-Hydroxyuridine
TL;DR: 5-Hydroxyuridine (CAS 957-77-7) is a chemical compound with molecular formula C9H12N2O7 and molecular weight 260.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione
Also Known As: 5-Hydroxyuridine, isobarbituridine, Uridine, 5-hydroxy-, 5-Oxouridine, OHUrd
| Molecular Formula | C9H12N2O7 |
|---|---|
| Molecular Weight | 260.06 g/mol |
| LogP | -2.1 |
| Topological Polar Surface Area | 140.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 260.06445 |
| Heavy Atoms | 18 |
| Complexity | 410.0 |
Chemical Identifiers
| CAS Number | 957-77-7 |
|---|---|
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O |
| InChIKey | QXDXBKZJFLRLCM-UAKXSSHOSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-Hydroxyuridine (CAS 957-77-7), with molecular formula C9H12N2O7 and molecular weight 260.06 g/mol. IUPAC: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione.
Chemical Property Profile of 5-Hydroxyuridine
Property Insights of 5-Hydroxyuridine
The XLogP value of -2.1 indicates that 5-Hydroxyuridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting 5-Hydroxyuridine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-Hydroxyuridine has 5 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Hydroxyuridine?
The CAS number of 5-Hydroxyuridine is 957-77-7.
What is the molecular formula of 5-Hydroxyuridine?
The molecular formula of 5-Hydroxyuridine is C9H12N2O7.
What is the molecular weight of 5-Hydroxyuridine?
The molecular weight of 5-Hydroxyuridine is 260.06 g/mol.
Where can I buy 5-Hydroxyuridine?
You can request a quote for 5-Hydroxyuridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Hydroxyuridine?
Yes, KEHONG BIO provides custom synthesis services for 5-Hydroxyuridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.