1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine
TL;DR: 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine (CAS 956784-97-7) is a chemical compound with molecular formula C13H10FN3S and molecular weight 259.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluorophenyl)-3-thiophen-2-ylpyrazol-5-amine
Also Known As: Maybridge3_006889, 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine, IDI1_018276, 1-(4-fluorophenyl)-3-thien-2-yl-1H-pyrazol-5-amine, 2-(4-fluorophenyl)-5-thiophen-2-ylpyrazol-3-amine
| Molecular Formula | C13H10FN3S |
|---|---|
| Molecular Weight | 259.06 g/mol |
| LogP | 3.3221 |
| Topological Polar Surface Area | 43.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 259.05795 |
| Heavy Atoms | 18 |
| Complexity | 656.1185 |
Chemical Identifiers
| CAS Number | 956784-97-7 |
|---|---|
| SMILES | C1=CSC(=C1)C2=NN(C(=C2)N)C3=CC=C(C=C3)F |
Product Overview
1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine (CAS 956784-97-7), with molecular formula C13H10FN3S and molecular weight 259.06 g/mol. IUPAC: 1-(4-fluorophenyl)-3-thiophen-2-ylpyrazol-5-amine.
Chemical Property Profile of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine
Property Insights of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine
The XLogP value of 3.3221 indicates that 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.84 Ų, 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine?
The CAS number of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine is 956784-97-7.
What is the molecular formula of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine?
The molecular formula of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine is C13H10FN3S.
What is the molecular weight of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine?
The molecular weight of 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine is 259.06 g/mol.
Where can I buy 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine?
You can request a quote for 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-fluorophenyl)-3-(thiophen-2-yl)-1H-pyrazol-5-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.