FGFR1 inhibitor-12
TL;DR: FGFR1 inhibitor-12 (CAS 956782-57-3) is a chemical compound with molecular formula C22H18ClFN2O3 and molecular weight 412.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(2-chloro-4-fluorophenyl)methyl]-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione
Also Known As: FGFR1 inhibitor-12, 3-(2-chloro-4-fluorobenzyl)-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione, 2,4-Imidazolidinedione, 3-[(2-chloro-4-fluorophenyl)methyl]-5-(6-methoxy-2-naphthalenyl)-5-methyl-, 3-[(2-chloro-4-fluorophenyl)methyl]-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione
| Molecular Formula | C22H18ClFN2O3 |
|---|---|
| Molecular Weight | 412.10 g/mol |
| LogP | 4.6081 |
| Topological Polar Surface Area | 58.64 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 412.099 |
| Heavy Atoms | 29 |
| Complexity | 1150.1056 |
Chemical Identifiers
| CAS Number | 956782-57-3 |
|---|---|
| SMILES | CC1(C(=O)N(C(=O)N1)CC2=C(C=C(C=C2)F)Cl)C3=CC4=C(C=C3)C=C(C=C4)OC |
Product Overview
FGFR1 inhibitor-12 (CAS 956782-57-3), with molecular formula C22H18ClFN2O3 and molecular weight 412.10 g/mol. IUPAC: 3-[(2-chloro-4-fluorophenyl)methyl]-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione.
Chemical Property Profile of FGFR1 inhibitor-12
Property Insights of FGFR1 inhibitor-12
The XLogP value of 4.6081 indicates that FGFR1 inhibitor-12 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.64 Ų, FGFR1 inhibitor-12 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, FGFR1 inhibitor-12 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of FGFR1 inhibitor-12?
The CAS number of FGFR1 inhibitor-12 is 956782-57-3.
What is the molecular formula of FGFR1 inhibitor-12?
The molecular formula of FGFR1 inhibitor-12 is C22H18ClFN2O3.
What is the molecular weight of FGFR1 inhibitor-12?
The molecular weight of FGFR1 inhibitor-12 is 412.10 g/mol.
Where can I buy FGFR1 inhibitor-12?
You can request a quote for FGFR1 inhibitor-12 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for FGFR1 inhibitor-12?
Yes, KEHONG BIO provides custom synthesis services for FGFR1 inhibitor-12 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.