8R-1154
TL;DR: 8R-1154 (CAS 956184-23-9) is a chemical compound with molecular formula C20H16Cl2F3N3O2 and molecular weight 457.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-N-[[5-chloro-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-N-(4-methoxyphenyl)benzamide
Also Known As: 8R-1154, 4-chloro-N-[[5-chloro-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-N-(4-methoxyphenyl)benzamide, 4-chloro-N-{[5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl}-N-(4-methoxyphenyl)benzenecarboxamide, 4-chloro-N-{[5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl}-N-(4-methoxyphenyl)benzamide
| Molecular Formula | C20H16Cl2F3N3O2 |
|---|---|
| Molecular Weight | 457.06 g/mol |
| LogP | 5.6013 |
| Topological Polar Surface Area | 47.36 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 457.05716 |
| Heavy Atoms | 30 |
| Complexity | 1048.8989 |
Chemical Identifiers
| CAS Number | 956184-23-9 |
|---|---|
| SMILES | CN1C(=C(C(=N1)C(F)(F)F)CN(C2=CC=C(C=C2)OC)C(=O)C3=CC=C(C=C3)Cl)Cl |
Product Overview
8R-1154 (CAS 956184-23-9), with molecular formula C20H16Cl2F3N3O2 and molecular weight 457.06 g/mol. IUPAC: 4-chloro-N-[[5-chloro-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-N-(4-methoxyphenyl)benzamide.
Chemical Property Profile of 8R-1154
Property Insights of 8R-1154
The XLogP value of 5.6013 indicates that 8R-1154 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.36 Ų, 8R-1154 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8R-1154 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8R-1154?
The CAS number of 8R-1154 is 956184-23-9.
What is the molecular formula of 8R-1154?
The molecular formula of 8R-1154 is C20H16Cl2F3N3O2.
What is the molecular weight of 8R-1154?
The molecular weight of 8R-1154 is 457.06 g/mol.
Where can I buy 8R-1154?
You can request a quote for 8R-1154 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8R-1154?
Yes, KEHONG BIO provides custom synthesis services for 8R-1154 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.