4-chloro-1H-1,5-naphthyridin-2-one
TL;DR: 4-chloro-1H-1,5-naphthyridin-2-one (CAS 95474-59-2) is a chemical compound with molecular formula C8H5ClN2O and molecular weight 180.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-1H-1,5-naphthyridin-2-one
Also Known As: 4-chloro-1,2-dihydro-1,5-naphthyridin-2-one, 4-chloro-1H-1,5-naphthyridin-2-one, 4-Chloro[1,5]naphthyridin-2-ol, 4-Chloro[1,5]naphthyridin-2-ol #, 4-Chloro-2-hydroxy-1,5-naphthyridine
| Molecular Formula | C8H5ClN2O |
|---|---|
| Molecular Weight | 180.01 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 42.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 180.00903 |
| Heavy Atoms | 12 |
| Complexity | 239.0 |
Chemical Identifiers
| CAS Number | 95474-59-2 |
|---|---|
| SMILES | C1=CC2=C(C(=CC(=O)N2)Cl)N=C1 |
| InChIKey | GEROIKVOSVNCRS-UHFFFAOYSA-N |
Product Overview
4-chloro-1H-1,5-naphthyridin-2-one (CAS 95474-59-2), with molecular formula C8H5ClN2O and molecular weight 180.01 g/mol. IUPAC: 4-chloro-1H-1,5-naphthyridin-2-one.
Chemical Property Profile of 4-chloro-1H-1,5-naphthyridin-2-one
Property Insights of 4-chloro-1H-1,5-naphthyridin-2-one
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-chloro-1H-1,5-naphthyridin-2-one. With a topological polar surface area (TPSA) of 42.0 Ų, 4-chloro-1H-1,5-naphthyridin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-chloro-1H-1,5-naphthyridin-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-chloro-1H-1,5-naphthyridin-2-one?
The CAS number of 4-chloro-1H-1,5-naphthyridin-2-one is 95474-59-2.
What is the molecular formula of 4-chloro-1H-1,5-naphthyridin-2-one?
The molecular formula of 4-chloro-1H-1,5-naphthyridin-2-one is C8H5ClN2O.
What is the molecular weight of 4-chloro-1H-1,5-naphthyridin-2-one?
The molecular weight of 4-chloro-1H-1,5-naphthyridin-2-one is 180.01 g/mol.
Where can I buy 4-chloro-1H-1,5-naphthyridin-2-one?
You can request a quote for 4-chloro-1H-1,5-naphthyridin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-chloro-1H-1,5-naphthyridin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-chloro-1H-1,5-naphthyridin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.