![1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone structure](/static/products/951/951945-88-3.png)
1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone
TL;DR: 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone (CAS 951945-88-3) is a chemical compound with molecular formula C18H17N3O2S and molecular weight 339.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(1H-indole-2-carbonyl)piperazin-1-yl]-thiophen-2-ylmethanone
Also Known As: 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone, (4-(1H-indole-2-carbonyl)piperazin-1-yl)(thiophen-2-yl)methanone
| Molecular Formula | C18H17N3O2S |
|---|---|
| Molecular Weight | 339.10 g/mol |
| LogP | 2.8276 |
| Topological Polar Surface Area | 56.41 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 339.10416 |
| Heavy Atoms | 24 |
| Complexity | 843.7059 |
Chemical Identifiers
| CAS Number | 951945-88-3 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC=CS2)C(=O)C3=CC4=CC=CC=C4N3 |
Product Overview
1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone (CAS 951945-88-3), with molecular formula C18H17N3O2S and molecular weight 339.10 g/mol. IUPAC: [4-(1H-indole-2-carbonyl)piperazin-1-yl]-thiophen-2-ylmethanone.
Chemical Property Profile of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone
Property Insights of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone
The XLogP value of 2.8276 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone. With a topological polar surface area (TPSA) of 56.41 Ų, 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone?
The CAS number of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone is 951945-88-3.
What is the molecular formula of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone?
The molecular formula of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone is C18H17N3O2S.
What is the molecular weight of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone?
The molecular weight of 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone is 339.10 g/mol.
Where can I buy 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone?
You can request a quote for 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for 1H-indol-2-yl[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.