Sornidipine
TL;DR: Sornidipine (CAS 95105-77-4) is a chemical compound with molecular formula C22H24N2O9 and molecular weight 460.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-[(3S,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Sornidipine, sornidipino, Sornidipine [INN], 5-O-[(3S,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 1,4:3,6-Dianhydro-5-O-[5-(methoxycarbonyl)-2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]-D-glucitol
| Molecular Formula | C22H24N2O9 |
|---|---|
| Molecular Weight | 460.15 g/mol |
| LogP | 1.0729 |
| Topological Polar Surface Area | 146.46 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 5 |
| Exact Mass | 460.1482 |
| Heavy Atoms | 33 |
| Complexity | 1063.7012 |
Chemical Identifiers
| CAS Number | 95105-77-4 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)O[C@@H]2CO[C@H]3[C@@H]2OC[C@@H]3O)C4=CC=CC=C4[N+](=O)[O-])C(=O)OC |
Product Overview
Sornidipine (CAS 95105-77-4), with molecular formula C22H24N2O9 and molecular weight 460.15 g/mol. IUPAC: 5-O-[(3S,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Sornidipine
Property Insights of Sornidipine
The XLogP value of 1.0729 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Sornidipine. The TPSA of 146.46 Ų indicates high polarity, suggesting Sornidipine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sornidipine has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sornidipine?
The CAS number of Sornidipine is 95105-77-4.
What is the molecular formula of Sornidipine?
The molecular formula of Sornidipine is C22H24N2O9.
What is the molecular weight of Sornidipine?
The molecular weight of Sornidipine is 460.15 g/mol.
Where can I buy Sornidipine?
You can request a quote for Sornidipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sornidipine?
Yes, KEHONG BIO provides custom synthesis services for Sornidipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.