22,23-dihydroavermectin B1(a) structure

22,23-dihydroavermectin B1(a)

TL;DR: 22,23-dihydroavermectin B1(a) (CAS 94837-49-7) is a chemical compound with molecular formula C48H75O17P and molecular weight 954.47 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2S,3S,4S,6S)-6-[(2S,3S,4S,6R)-6-[(1R,4S,5'S,6R,6'R,8R,10E,12R,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxospiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-12-yl]oxy-4-methoxy-2-methyloxan-3-yl]oxy-4-methoxy-2-methyloxan-3-yl] dihydrogen phosphate

Also Known As: IVMPO4, H2B1a avermectin, Dihydroivermectin B1a, 22,23-Dihydroavermectin B1(a), 22,23-Dihydroavermectin B(1)a

CAS: 94837-49-7
Molecular Formula C48H75O17P
Molecular Weight 954.47 g/mol
LogP 5.7184
Topological Polar Surface Area 216.59 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 15
Rotatable Bonds 10
Exact Mass 954.4742
Heavy Atoms 66
Complexity 1862.1218

Chemical Identifiers

CAS Number 94837-49-7
SMILES CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)OP(=O)(O)O)OC)OC)\C)C

Product Overview

22,23-dihydroavermectin B1(a) (CAS 94837-49-7), with molecular formula C48H75O17P and molecular weight 954.47 g/mol. IUPAC: [(2S,3S,4S,6S)-6-[(2S,3S,4S,6R)-6-[(1R,4S,5'S,6R,6'R,8R,10E,12R,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxospiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-12-yl]oxy-4-methoxy-2-methyloxan-3-yl]oxy-4-methoxy-2-methyloxan-3-yl] dihydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 22,23-dihydroavermectin B1(a)

XLogP
5.7184
TPSA (Topological Polar Surface Area)
216.59
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
15
Rotatable Bonds
10
Heavy Atoms
66
Complexity
1862.1218
Exact Mass
954.4742
Monoisotopic Mass
954.4742
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 22,23-dihydroavermectin B1(a)

The XLogP value of 5.7184 indicates that 22,23-dihydroavermectin B1(a) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 216.59 Ų indicates high polarity, suggesting 22,23-dihydroavermectin B1(a) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 22,23-dihydroavermectin B1(a) has 4 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 22,23-dihydroavermectin B1(a)?

The CAS number of 22,23-dihydroavermectin B1(a) is 94837-49-7.

What is the molecular formula of 22,23-dihydroavermectin B1(a)?

The molecular formula of 22,23-dihydroavermectin B1(a) is C48H75O17P.

What is the molecular weight of 22,23-dihydroavermectin B1(a)?

The molecular weight of 22,23-dihydroavermectin B1(a) is 954.47 g/mol.

Where can I buy 22,23-dihydroavermectin B1(a)?

You can request a quote for 22,23-dihydroavermectin B1(a) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 22,23-dihydroavermectin B1(a)?

Yes, KEHONG BIO provides custom synthesis services for 22,23-dihydroavermectin B1(a) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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