Levcromakalim
TL;DR: Levcromakalim (CAS 94535-50-9) is a chemical compound with molecular formula C16H18N2O3 and molecular weight 286.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile
Also Known As: Levcromakalim, Cromakalim, Lemakalim, (-)-Cromakalim, Levcromakelim
| Molecular Formula | C16H18N2O3 |
|---|---|
| Molecular Weight | 286.13 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 73.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 286.13174 |
| Heavy Atoms | 21 |
| Complexity | 481.0 |
Chemical Identifiers
| CAS Number | 94535-50-9 |
|---|---|
| SMILES | CC1([C@H]([C@@H](C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C |
| InChIKey | TVZCRIROJQEVOT-CABCVRRESA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Levcromakalim (CAS 94535-50-9), with molecular formula C16H18N2O3 and molecular weight 286.13 g/mol. IUPAC: (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile.
Chemical Property Profile of Levcromakalim
Property Insights of Levcromakalim
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Levcromakalim. The TPSA of 73.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Levcromakalim. Following Lipinski's Rule of Five, Levcromakalim has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Levcromakalim?
The CAS number of Levcromakalim is 94535-50-9.
What is the molecular formula of Levcromakalim?
The molecular formula of Levcromakalim is C16H18N2O3.
What is the molecular weight of Levcromakalim?
The molecular weight of Levcromakalim is 286.13 g/mol.
Where can I buy Levcromakalim?
You can request a quote for Levcromakalim directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Levcromakalim?
Yes, KEHONG BIO provides custom synthesis services for Levcromakalim and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.