(+)-Cromakalim
TL;DR: (+)-Cromakalim (CAS 94470-67-4) is a chemical compound with molecular formula C16H18N2O3 and molecular weight 286.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,4S)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile
Also Known As: Cromakalim, Cromakalin, (+)-Cromakalim, Levcromakalim, Cromakalime
| Molecular Formula | C16H18N2O3 |
|---|---|
| Molecular Weight | 286.13 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 73.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 286.13174 |
| Heavy Atoms | 21 |
| Complexity | 481.0 |
Chemical Identifiers
| CAS Number | 94470-67-4 |
|---|---|
| SMILES | CC1([C@@H]([C@H](C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C |
| InChIKey | TVZCRIROJQEVOT-LSDHHAIUSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(+)-Cromakalim (CAS 94470-67-4), with molecular formula C16H18N2O3 and molecular weight 286.13 g/mol. IUPAC: (3R,4S)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile.
Chemical Property Profile of (+)-Cromakalim
Property Insights of (+)-Cromakalim
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (+)-Cromakalim. The TPSA of 73.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (+)-Cromakalim. Following Lipinski's Rule of Five, (+)-Cromakalim has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Cromakalim?
The CAS number of (+)-Cromakalim is 94470-67-4.
What is the molecular formula of (+)-Cromakalim?
The molecular formula of (+)-Cromakalim is C16H18N2O3.
What is the molecular weight of (+)-Cromakalim?
The molecular weight of (+)-Cromakalim is 286.13 g/mol.
Where can I buy (+)-Cromakalim?
You can request a quote for (+)-Cromakalim directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Cromakalim?
Yes, KEHONG BIO provides custom synthesis services for (+)-Cromakalim and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.