F2744-1227
TL;DR: F2744-1227 (CAS 942009-68-9) is a chemical compound with molecular formula C20H13F5N2O2 and molecular weight 408.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2,5-difluorophenyl)-6-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
Also Known As: F2744-1227, N-(2,5-difluorophenyl)-6-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide, N-(2,5-difluorophenyl)-6-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide, N-(2,5-difluorophenyl)-6-oxo-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide
| Molecular Formula | C20H13F5N2O2 |
|---|---|
| Molecular Weight | 408.09 g/mol |
| LogP | 4.4459 |
| Topological Polar Surface Area | 51.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 408.08972 |
| Heavy Atoms | 29 |
| Complexity | 1122.3398 |
Chemical Identifiers
| CAS Number | 942009-68-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)CN2C=C(C=CC2=O)C(=O)NC3=C(C=CC(=C3)F)F |
Product Overview
F2744-1227 (CAS 942009-68-9), with molecular formula C20H13F5N2O2 and molecular weight 408.09 g/mol. IUPAC: N-(2,5-difluorophenyl)-6-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide.
Chemical Property Profile of F2744-1227
Property Insights of F2744-1227
The XLogP value of 4.4459 indicates that F2744-1227 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.1 Ų, F2744-1227 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F2744-1227 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F2744-1227?
The CAS number of F2744-1227 is 942009-68-9.
What is the molecular formula of F2744-1227?
The molecular formula of F2744-1227 is C20H13F5N2O2.
What is the molecular weight of F2744-1227?
The molecular weight of F2744-1227 is 408.09 g/mol.
Where can I buy F2744-1227?
You can request a quote for F2744-1227 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F2744-1227?
Yes, KEHONG BIO provides custom synthesis services for F2744-1227 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.