(-)-Devapamil
TL;DR: (-)-Devapamil (CAS 93468-87-2) is a chemical compound with molecular formula C26H36N2O3 and molecular weight 424.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3-methoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
Also Known As: (-)-Devapamil, Devapamil, 4-Desmethoxyverapamil, (-)-Desmethoxyverapamil, Desmethoxyverapamil
| Molecular Formula | C26H36N2O3 |
|---|---|
| Molecular Weight | 424.27 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 54.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 12 |
| Exact Mass | 424.27258 |
| Heavy Atoms | 31 |
| Complexity | 560.0 |
Chemical Identifiers
| CAS Number | 93468-87-2 |
|---|---|
| SMILES | CC(C)[C@](CCCN(C)CCC1=CC(=CC=C1)OC)(C#N)C2=CC(=C(C=C2)OC)OC |
| InChIKey | VMVKIDPOEOLUFS-SANMLTNESA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(-)-Devapamil (CAS 93468-87-2), with molecular formula C26H36N2O3 and molecular weight 424.27 g/mol. IUPAC: (2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3-methoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile.
Chemical Property Profile of (-)-Devapamil
Property Insights of (-)-Devapamil
The XLogP value of 3.8 indicates that (-)-Devapamil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.7 Ų, (-)-Devapamil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (-)-Devapamil has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-Devapamil?
The CAS number of (-)-Devapamil is 93468-87-2.
What is the molecular formula of (-)-Devapamil?
The molecular formula of (-)-Devapamil is C26H36N2O3.
What is the molecular weight of (-)-Devapamil?
The molecular weight of (-)-Devapamil is 424.27 g/mol.
Where can I buy (-)-Devapamil?
You can request a quote for (-)-Devapamil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-Devapamil?
Yes, KEHONG BIO provides custom synthesis services for (-)-Devapamil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.