依維莫司
TL;DR: 依維莫司 (CAS 934660-93-2) is a chemical compound with molecular formula C53H83NO14 and molecular weight 957.58 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
依維莫司
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Also Known As: Everolimus, Afinitor, Certican, Zortress, Votubia
| Molecular Formula | C53H83NO14 |
|---|---|
| Molecular Weight | 957.58 g/mol |
| LogP | 6.1972 |
| Topological Polar Surface Area | 204.66 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 9 |
| Exact Mass | 957.58136 |
| Heavy Atoms | 68 |
| Complexity | 1809.0647 |
Chemical Identifiers
| CAS Number | 934660-93-2 |
|---|---|
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC |
Product Overview
依維莫司 (CAS 934660-93-2), with molecular formula C53H83NO14 and molecular weight 957.58 g/mol. IUPAC: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone.
Chemical Property Profile of 依維莫司
Property Insights of 依維莫司
The XLogP value of 6.1972 indicates that 依維莫司 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 204.66 Ų indicates high polarity, suggesting 依維莫司 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 依維莫司 has 3 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 依維莫司?
The CAS number of 依維莫司 is 934660-93-2.
What is the molecular formula of 依維莫司?
The molecular formula of 依維莫司 is C53H83NO14.
What is the molecular weight of 依維莫司?
The molecular weight of 依維莫司 is 957.58 g/mol.
Where can I buy 依維莫司?
You can request a quote for 依維莫司 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 依維莫司?
Yes, KEHONG BIO provides custom synthesis services for 依維莫司 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.