4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine
TL;DR: 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine (CAS 93181-89-6) is a chemical compound with molecular formula C16H16F3N3O and molecular weight 323.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-piperidin-1-yl-6-(trifluoromethyl)pyrimidin-2-yl]phenol
Also Known As: 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine, 2-(2-Hydroxyphenyl)-4-piperidino-6-(trifluoromethyl)pyrimidine, 2-(2-HYDROXYPHENYL)-4-PIPERIDINO-6-TRIFLUOROMETHYLPYRIMIDINE, 2-[4-(1-Piperidinyl)-6-(trifluoromethyl)-2-pyrimidinyl]phenol #, 2-[4-(piperidin-1-yl)-6-(trifluoromethyl)pyrimidin-2-yl]phenol
| Molecular Formula | C16H16F3N3O |
|---|---|
| Molecular Weight | 323.12 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 49.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 323.12454 |
| Heavy Atoms | 23 |
| Complexity | 387.0 |
Chemical Identifiers
| CAS Number | 93181-89-6 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC(=NC(=C2)C(F)(F)F)C3=CC=CC=C3O |
| InChIKey | VWGOMZPDBSWHRL-UHFFFAOYSA-N |
Product Overview
4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine (CAS 93181-89-6), with molecular formula C16H16F3N3O and molecular weight 323.12 g/mol. IUPAC: 2-[4-piperidin-1-yl-6-(trifluoromethyl)pyrimidin-2-yl]phenol.
Chemical Property Profile of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine
Property Insights of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine
The XLogP value of 3.7 indicates that 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.3 Ų, 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine?
The CAS number of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine is 93181-89-6.
What is the molecular formula of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine?
The molecular formula of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine is C16H16F3N3O.
What is the molecular weight of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine?
The molecular weight of 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine is 323.12 g/mol.
Where can I buy 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine?
You can request a quote for 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 4-Piperidino-6-trifluoromethyl-2-(2-hydroxyphenyl)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.