Ro 15-5458
TL;DR: Ro 15-5458 (CAS 92928-47-7) is a chemical compound with molecular formula C22H27N5S and molecular weight 393.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[[10-[2-(diethylamino)ethyl]acridin-9-ylidene]amino]-4,5-dihydro-1,3-thiazol-2-amine
Also Known As: Ro 15-5458, Ro-15-5458, Ro15-5458, 10-(2-9 -acridinone hydrazone, 10-(2- -9 -acridinone hydrazone
| Molecular Formula | C22H27N5S |
|---|---|
| Molecular Weight | 393.20 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 68.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 393.19873 |
| Heavy Atoms | 28 |
| Complexity | 547.0 |
Chemical Identifiers
| CAS Number | 92928-47-7 |
|---|---|
| SMILES | CCN(CC)CCN1C2=CC=CC=C2C(=NNC3=NCCS3)C4=CC=CC=C41 |
| InChIKey | OFJBLFHGVVUQEU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Ro 15-5458 (CAS 92928-47-7), with molecular formula C22H27N5S and molecular weight 393.20 g/mol. IUPAC: N-[[10-[2-(diethylamino)ethyl]acridin-9-ylidene]amino]-4,5-dihydro-1,3-thiazol-2-amine.
Chemical Property Profile of Ro 15-5458
Property Insights of Ro 15-5458
The XLogP value of 4.3 indicates that Ro 15-5458 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Ro 15-5458. Following Lipinski's Rule of Five, Ro 15-5458 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ro 15-5458?
The CAS number of Ro 15-5458 is 92928-47-7.
What is the molecular formula of Ro 15-5458?
The molecular formula of Ro 15-5458 is C22H27N5S.
What is the molecular weight of Ro 15-5458?
The molecular weight of Ro 15-5458 is 393.20 g/mol.
Where can I buy Ro 15-5458?
You can request a quote for Ro 15-5458 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ro 15-5458?
Yes, KEHONG BIO provides custom synthesis services for Ro 15-5458 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.