Zidovudine triphosphate
TL;DR: Zidovudine triphosphate (CAS 92586-35-1) is a chemical compound with molecular formula C10H16N5O13P3 and molecular weight 507.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Also Known As: AZT triphosphate, Zidovudine triphosphate, Combivir, AZTTP, Azt-TP
| Molecular Formula | C10H16N5O13P3 |
|---|---|
| Molecular Weight | 507.00 g/mol |
| LogP | -3.2 |
| Topological Polar Surface Area | 233.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 9 |
| Exact Mass | 506.99576 |
| Heavy Atoms | 31 |
| Complexity | 973.0 |
Chemical Identifiers
| CAS Number | 92586-35-1 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-] |
| InChIKey | GLWHPRRGGYLLRV-XLPZGREQSA-N |
Product Overview
Zidovudine triphosphate (CAS 92586-35-1), with molecular formula C10H16N5O13P3 and molecular weight 507.00 g/mol. IUPAC: [[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate.
Chemical Property Profile of Zidovudine triphosphate
Property Insights of Zidovudine triphosphate
The XLogP value of -3.2 indicates that Zidovudine triphosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 233.0 Ų indicates high polarity, suggesting Zidovudine triphosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Zidovudine triphosphate has 5 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Zidovudine triphosphate?
The CAS number of Zidovudine triphosphate is 92586-35-1.
What is the molecular formula of Zidovudine triphosphate?
The molecular formula of Zidovudine triphosphate is C10H16N5O13P3.
What is the molecular weight of Zidovudine triphosphate?
The molecular weight of Zidovudine triphosphate is 507.00 g/mol.
Where can I buy Zidovudine triphosphate?
You can request a quote for Zidovudine triphosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Zidovudine triphosphate?
Yes, KEHONG BIO provides custom synthesis services for Zidovudine triphosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.