Aprikalim
TL;DR: Aprikalim (CAS 92569-65-8) is a chemical compound with molecular formula C12H16N2OS2 and molecular weight 268.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,2R)-N-methyl-1-oxo-2-pyridin-3-ylthiane-2-carbothioamide
Also Known As: Aprikalim, Aprikalimum, Aprim, Aprikalim [INN], Aprikalimum [INN-Latin]
| Molecular Formula | C12H16N2OS2 |
|---|---|
| Molecular Weight | 268.07 g/mol |
| LogP | 1.7563 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 268.0704 |
| Heavy Atoms | 17 |
| Complexity | 425.39157 |
Chemical Identifiers
| CAS Number | 92569-65-8 |
|---|---|
| SMILES | CNC(=S)[C@@]1(CCCC[S@]1=O)C2=CN=CC=C2 |
Product Overview
Aprikalim (CAS 92569-65-8), with molecular formula C12H16N2OS2 and molecular weight 268.07 g/mol. IUPAC: (1R,2R)-N-methyl-1-oxo-2-pyridin-3-ylthiane-2-carbothioamide.
Chemical Property Profile of Aprikalim
Property Insights of Aprikalim
The XLogP value of 1.7563 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Aprikalim. With a topological polar surface area (TPSA) of 41.99 Ų, Aprikalim exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Aprikalim has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Aprikalim?
The CAS number of Aprikalim is 92569-65-8.
What is the molecular formula of Aprikalim?
The molecular formula of Aprikalim is C12H16N2OS2.
What is the molecular weight of Aprikalim?
The molecular weight of Aprikalim is 268.07 g/mol.
Where can I buy Aprikalim?
You can request a quote for Aprikalim directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Aprikalim?
Yes, KEHONG BIO provides custom synthesis services for Aprikalim and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.