5-fam-nhs structure

5-fam-nhs

TL;DR: 5-fam-nhs (CAS 92557-80-7) is a chemical compound with molecular formula C25H15NO9 and molecular weight 473.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid

Also Known As: 5-fam-nhs, 5-carboxyfluorescein se, 5-FAM SE, 5-Carboxyfluorescein-NHS, 5-FAMSE

CAS: 92557-80-7
Molecular Formula C25H15NO9
Molecular Weight 473.07 g/mol
LogP 3.1894
Topological Polar Surface Area 151.42 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 8
Rotatable Bonds 4
Exact Mass 473.07468
Heavy Atoms 35
Complexity 1584.6392

Chemical Identifiers

CAS Number 92557-80-7
SMILES C1CC(=O)N(C1=O)OC(=O)C2=CC(=C(C=C2)C3=C4C=CC(=O)C=C4OC5=C3C=CC(=C5)O)C(=O)O

Product Overview

5-fam-nhs (CAS 92557-80-7), with molecular formula C25H15NO9 and molecular weight 473.07 g/mol. IUPAC: 5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 5-fam-nhs

XLogP
3.1894
TPSA (Topological Polar Surface Area)
151.42
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
8
Rotatable Bonds
4
Heavy Atoms
35
Complexity
1584.6392
Exact Mass
473.07468
Monoisotopic Mass
473.07468
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-fam-nhs

The XLogP value of 3.1894 indicates that 5-fam-nhs is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 151.42 Ų indicates high polarity, suggesting 5-fam-nhs may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-fam-nhs has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-fam-nhs?

The CAS number of 5-fam-nhs is 92557-80-7.

What is the molecular formula of 5-fam-nhs?

The molecular formula of 5-fam-nhs is C25H15NO9.

What is the molecular weight of 5-fam-nhs?

The molecular weight of 5-fam-nhs is 473.07 g/mol.

Where can I buy 5-fam-nhs?

You can request a quote for 5-fam-nhs directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-fam-nhs?

Yes, KEHONG BIO provides custom synthesis services for 5-fam-nhs and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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