conotoxin GI, des-Glu(1)-
TL;DR: conotoxin GI, des-Glu(1)- (CAS 92137-82-1) is a chemical compound with molecular formula C50H73N19O15S4 and molecular weight 1307.44 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,7S,10S,13S,16S,19R,24R,27S,33S,36S,43R)-43-amino-27-(2-amino-2-oxoethyl)-7-[3-(diaminomethylideneamino)propyl]-16-(hydroxymethyl)-13-[(4-hydroxyphenyl)methyl]-10-(1H-imidazol-5-ylmethyl)-36-methyl-2,5,8,11,14,17,25,28,34,37,44-undecaoxo-21,22,40,41-tetrathia-3,6,9,12,15,18,26,29,35,38,45-undecazatricyclo[22.14.7.029,33]pentatetracontane-19-carboxamide
Also Known As: Conotoxin GI, des-glu(1)-, Des-glu(1)-conotoxin GI, Conotoxin G1 (reduced), 1-de-L-glutamic acid-, cyclic (2-7),(3-13)-bis(disulfide), RefChem:127804
| Molecular Formula | C50H73N19O15S4 |
|---|---|
| Molecular Weight | 1307.44 g/mol |
| LogP | -7.0 |
| Topological Polar Surface Area | 658.0 Ų |
| Hydrogen Bond Donors | 18 |
| Hydrogen Bond Acceptors | 22 |
| Rotatable Bonds | 12 |
| Exact Mass | 1307.4417 |
| Heavy Atoms | 88 |
| Complexity | 2550.0 |
Chemical Identifiers
| CAS Number | 92137-82-1 |
|---|---|
| SMILES | C[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC2=O)CCCN=C(N)N)CC3=CN=CN3)CC4=CC=C(C=C4)O)CO)C(=O)N)C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N1)CC(=O)N)N |
| InChIKey | FTMXUWWSNKVHRM-XCNZWTKDSA-N |
Product Overview
conotoxin GI, des-Glu(1)- (CAS 92137-82-1), with molecular formula C50H73N19O15S4 and molecular weight 1307.44 g/mol. IUPAC: (1R,7S,10S,13S,16S,19R,24R,27S,33S,36S,43R)-43-amino-27-(2-amino-2-oxoethyl)-7-[3-(diaminomethylideneamino)propyl]-16-(hydroxymethyl)-13-[(4-hydroxyphenyl)methyl]-10-(1H-imidazol-5-ylmethyl)-36-methyl-2,5,8,11,14,17,25,28,34,37,44-undecaoxo-21,22,40,41-tetrathia-3,6,9,12,15,18,26,29,35,38,45-undecazatricyclo[22.14.7.029,33]pentatetracontane-19-carboxamide.
Chemical Property Profile of conotoxin GI, des-Glu(1)-
Property Insights of conotoxin GI, des-Glu(1)-
The XLogP value of -7.0 indicates that conotoxin GI, des-Glu(1)- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 658.0 Ų indicates high polarity, suggesting conotoxin GI, des-Glu(1)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, conotoxin GI, des-Glu(1)- has 18 hydrogen bond donor(s) and 22 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of conotoxin GI, des-Glu(1)-?
The CAS number of conotoxin GI, des-Glu(1)- is 92137-82-1.
What is the molecular formula of conotoxin GI, des-Glu(1)-?
The molecular formula of conotoxin GI, des-Glu(1)- is C50H73N19O15S4.
What is the molecular weight of conotoxin GI, des-Glu(1)-?
The molecular weight of conotoxin GI, des-Glu(1)- is 1307.44 g/mol.
Where can I buy conotoxin GI, des-Glu(1)-?
You can request a quote for conotoxin GI, des-Glu(1)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for conotoxin GI, des-Glu(1)-?
Yes, KEHONG BIO provides custom synthesis services for conotoxin GI, des-Glu(1)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.