4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol
TL;DR: 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol (CAS 91606-60-9) is a chemical compound with molecular formula C6H5F3N2O and molecular weight 178.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-methyl-4-(trifluoromethyl)-1H-pyrimidin-2-one
Also Known As: 4-methyl-6-(trifluoromethyl)pyrimidin-2-ol, 4-Methyl-6-(trifluoromethyl)pyrimidin-2(1H)-one, 4-methyl-6-(trifluoromethyl)-2-pyrimidinol, 6-methyl-4-(trifluoromethyl)-1H-pyrimidin-2-one, ZERO/006136
| Molecular Formula | C6H5F3N2O |
|---|---|
| Molecular Weight | 178.04 g/mol |
| LogP | 1.09712 |
| Topological Polar Surface Area | 45.75 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 178.0354 |
| Heavy Atoms | 12 |
| Complexity | 341.3818 |
Chemical Identifiers
| CAS Number | 91606-60-9 |
|---|---|
| SMILES | CC1=CC(=NC(=O)N1)C(F)(F)F |
Product Overview
4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol (CAS 91606-60-9), with molecular formula C6H5F3N2O and molecular weight 178.04 g/mol. IUPAC: 6-methyl-4-(trifluoromethyl)-1H-pyrimidin-2-one.
Chemical Property Profile of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol
Property Insights of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol
The XLogP value of 1.09712 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol. With a topological polar surface area (TPSA) of 45.75 Ų, 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol?
The CAS number of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol is 91606-60-9.
What is the molecular formula of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol?
The molecular formula of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol is C6H5F3N2O.
What is the molecular weight of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol?
The molecular weight of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol is 178.04 g/mol.
Where can I buy 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol?
You can request a quote for 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol?
Yes, KEHONG BIO provides custom synthesis services for 4-Methyl-6-(trifluoromethyl)pyrimidin-2-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.