noscapine
TL;DR: noscapine (CAS 912-60-7) is a chemical compound with molecular formula C22H24ClNO7 and molecular weight 449.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-2-benzofuran-1-one chloride
Also Known As: noscapine, Narcotussin, Tusscapine, Longatin, Tucotine
| Molecular Formula | C22H24ClNO7 |
|---|---|
| Molecular Weight | 449.12 g/mol |
| LogP | -1.53 |
| Topological Polar Surface Area | 76.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 449.1241 |
| Heavy Atoms | 31 |
| Complexity | 647.0 |
Chemical Identifiers
| CAS Number | 912-60-7 |
|---|---|
| SMILES | C[NH+]1CCC2=CC3=C(C(=C2[C@H]1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.[Cl-] |
| InChIKey | MFLVZFXCSKVCSH-OQICONIUSA-N |
Product Overview
noscapine (CAS 912-60-7), with molecular formula C22H24ClNO7 and molecular weight 449.12 g/mol. IUPAC: 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-2-benzofuran-1-one chloride.
Chemical Property Profile of noscapine
Property Insights of noscapine
The XLogP value of -1.53 indicates that noscapine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 76.9 Ų falls within the moderate polarity range, balancing permeability and solubility for noscapine. Following Lipinski's Rule of Five, noscapine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of noscapine?
The CAS number of noscapine is 912-60-7.
What is the molecular formula of noscapine?
The molecular formula of noscapine is C22H24ClNO7.
What is the molecular weight of noscapine?
The molecular weight of noscapine is 449.12 g/mol.
Where can I buy noscapine?
You can request a quote for noscapine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for noscapine?
Yes, KEHONG BIO provides custom synthesis services for noscapine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.