5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one
TL;DR: 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one (CAS 91021-08-8) is a chemical compound with molecular formula C16H12FNO3 and molecular weight 285.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-3-hydroxy-3-phenacyl-1H-indol-2-one
Also Known As: EiM08-08235, 5-fluoro-3-hydroxy-3-phenacyl-1H-indol-2-one, 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one, 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)indolin-2-one, 5-FLUORO-3-HYDROXY-3-(2-OXO-2-PHENYLETHYL)-2,3-DIHYDRO-1H-INDOL-2-ONE
| Molecular Formula | C16H12FNO3 |
|---|---|
| Molecular Weight | 285.08 g/mol |
| LogP | 2.2384 |
| Topological Polar Surface Area | 66.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 285.0801 |
| Heavy Atoms | 21 |
| Complexity | 729.5569 |
Chemical Identifiers
| CAS Number | 91021-08-8 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(=O)CC2(C3=C(C=CC(=C3)F)NC2=O)O |
Product Overview
5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one (CAS 91021-08-8), with molecular formula C16H12FNO3 and molecular weight 285.08 g/mol. IUPAC: 5-fluoro-3-hydroxy-3-phenacyl-1H-indol-2-one.
Chemical Property Profile of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one
Property Insights of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one
The XLogP value of 2.2384 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one. Following Lipinski's Rule of Five, 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one?
The CAS number of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one is 91021-08-8.
What is the molecular formula of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one?
The molecular formula of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one is C16H12FNO3.
What is the molecular weight of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one?
The molecular weight of 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one is 285.08 g/mol.
Where can I buy 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one?
You can request a quote for 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-fluoro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.