![2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine structure](/static/products/908/908228-28-4.png)
2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine
TL;DR: 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine (CAS 908228-28-4) is a chemical compound with molecular formula C21H27N5O2S and molecular weight 413.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(3,5-dimethylpyrazol-1-yl)-12,12-dimethyl-N-(oxolan-2-ylmethyl)-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6-tetraen-3-amine
Also Known As: 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-(tetrahydrofuran-2-ylmethyl)-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine
| Molecular Formula | C21H27N5O2S |
|---|---|
| Molecular Weight | 413.19 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 102.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 413.18854 |
| Heavy Atoms | 29 |
| Complexity | 595.0 |
Chemical Identifiers
| CAS Number | 908228-28-4 |
|---|---|
| SMILES | CC1=CC(=NN1C2=NC(=C3C4=C(COC(C4)(C)C)SC3=N2)NCC5CCCO5)C |
| InChIKey | XPTWRFXBXFWANW-UHFFFAOYSA-N |
Product Overview
2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine (CAS 908228-28-4), with molecular formula C21H27N5O2S and molecular weight 413.19 g/mol. IUPAC: 5-(3,5-dimethylpyrazol-1-yl)-12,12-dimethyl-N-(oxolan-2-ylmethyl)-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6-tetraen-3-amine.
Chemical Property Profile of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine
Property Insights of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine
The XLogP value of 3.7 indicates that 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine. Following Lipinski's Rule of Five, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine?
The CAS number of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine is 908228-28-4.
What is the molecular formula of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine?
The molecular formula of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine is C21H27N5O2S.
What is the molecular weight of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine?
The molecular weight of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine is 413.19 g/mol.
Where can I buy 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine?
You can request a quote for 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6,6-dimethyl-N-((tetrahydrofuran-2-yl)methyl)-6,8-dihydro-5H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.