21-Amino-17-hydroxyprogesterone
TL;DR: 21-Amino-17-hydroxyprogesterone (CAS 908-82-7) is a chemical compound with molecular formula C21H32ClNO3 and molecular weight 381.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13S,14S,17R)-17-(2-aminoacetyl)-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;hydrochloride
Also Known As: 21-amino-17-hydroxyprogesterone hydrochloride, 21-A-17-Ohp, 21-Amino-17-hydroxyprogesterone, 21-Amino-17-hydroxyprogesteronehydrochloride, 21-Amino-17-hydroxy-4-pregnene-3,20-dione
| Molecular Formula | C21H32ClNO3 |
|---|---|
| Molecular Weight | 381.21 g/mol |
| LogP | 3.199 |
| Topological Polar Surface Area | 80.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 381.20706 |
| Heavy Atoms | 26 |
| Complexity | 656.0 |
Chemical Identifiers
| CAS Number | 908-82-7 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4(C(=O)CN)O)C.Cl |
| InChIKey | VVHIFFRVNVWIOK-CBJHTUOLSA-N |
Product Overview
21-Amino-17-hydroxyprogesterone (CAS 908-82-7), with molecular formula C21H32ClNO3 and molecular weight 381.21 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-17-(2-aminoacetyl)-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;hydrochloride.
Chemical Property Profile of 21-Amino-17-hydroxyprogesterone
Property Insights of 21-Amino-17-hydroxyprogesterone
The XLogP value of 3.199 indicates that 21-Amino-17-hydroxyprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 21-Amino-17-hydroxyprogesterone. Following Lipinski's Rule of Five, 21-Amino-17-hydroxyprogesterone has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 21-Amino-17-hydroxyprogesterone?
The CAS number of 21-Amino-17-hydroxyprogesterone is 908-82-7.
What is the molecular formula of 21-Amino-17-hydroxyprogesterone?
The molecular formula of 21-Amino-17-hydroxyprogesterone is C21H32ClNO3.
What is the molecular weight of 21-Amino-17-hydroxyprogesterone?
The molecular weight of 21-Amino-17-hydroxyprogesterone is 381.21 g/mol.
Where can I buy 21-Amino-17-hydroxyprogesterone?
You can request a quote for 21-Amino-17-hydroxyprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 21-Amino-17-hydroxyprogesterone?
Yes, KEHONG BIO provides custom synthesis services for 21-Amino-17-hydroxyprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.