EGFR inhibitor
TL;DR: EGFR inhibitor (CAS 907952-06-1) is a chemical compound with molecular formula C21H18F3N5O and molecular weight 413.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide
Also Known As: EGFR Inhibitor, EGFR-IN-12, EGFR?Inhibitor, EGFR Blocker, EGFR-TK Inhibitor
| Molecular Formula | C21H18F3N5O |
|---|---|
| Molecular Weight | 413.15 g/mol |
| LogP | 5.3311 |
| Topological Polar Surface Area | 78.94 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 413.14633 |
| Heavy Atoms | 30 |
| Complexity | 1066.2576 |
Chemical Identifiers
| CAS Number | 907952-06-1 |
|---|---|
| SMILES | C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=NC(=C3)NC4=CC=CC(=C4)C(F)(F)F |
Product Overview
EGFR inhibitor (CAS 907952-06-1), with molecular formula C21H18F3N5O and molecular weight 413.15 g/mol. IUPAC: N-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide.
Chemical Property Profile of EGFR inhibitor
Property Insights of EGFR inhibitor
The XLogP value of 5.3311 indicates that EGFR inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.94 Ų falls within the moderate polarity range, balancing permeability and solubility for EGFR inhibitor. Following Lipinski's Rule of Five, EGFR inhibitor has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of EGFR inhibitor?
The CAS number of EGFR inhibitor is 907952-06-1.
What is the molecular formula of EGFR inhibitor?
The molecular formula of EGFR inhibitor is C21H18F3N5O.
What is the molecular weight of EGFR inhibitor?
The molecular weight of EGFR inhibitor is 413.15 g/mol.
Where can I buy EGFR inhibitor?
You can request a quote for EGFR inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for EGFR inhibitor?
Yes, KEHONG BIO provides custom synthesis services for EGFR inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.