4-Chloro-5-fluoro-2-methylpyrimidine
TL;DR: 4-Chloro-5-fluoro-2-methylpyrimidine (CAS 90772-35-3) is a chemical compound with molecular formula C5H4ClFN2 and molecular weight 146.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-5-fluoro-2-methylpyrimidine
Also Known As: 4-Chloro-5-fluoro-2-methylpyrimidine, 4-chloro-5-fluoro-2-methyl-pyrimidine, 1-methyl-5-nitroindole, fluoro-chloro-methyl pyrimidine, 5-Fluoro-4-chloro-2-methylpyrimidine
| Molecular Formula | C5H4ClFN2 |
|---|---|
| Molecular Weight | 146.00 g/mol |
| LogP | 1.7 |
| Topological Polar Surface Area | 25.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 146.0047 |
| Heavy Atoms | 9 |
| Complexity | 101.0 |
Chemical Identifiers
| CAS Number | 90772-35-3 |
|---|---|
| SMILES | CC1=NC=C(C(=N1)Cl)F |
| InChIKey | QSFGQHQXDKLATK-UHFFFAOYSA-N |
Product Overview
4-Chloro-5-fluoro-2-methylpyrimidine (CAS 90772-35-3), with molecular formula C5H4ClFN2 and molecular weight 146.00 g/mol. IUPAC: 4-chloro-5-fluoro-2-methylpyrimidine.
Chemical Property Profile of 4-Chloro-5-fluoro-2-methylpyrimidine
Property Insights of 4-Chloro-5-fluoro-2-methylpyrimidine
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Chloro-5-fluoro-2-methylpyrimidine. With a topological polar surface area (TPSA) of 25.8 Ų, 4-Chloro-5-fluoro-2-methylpyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-5-fluoro-2-methylpyrimidine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-5-fluoro-2-methylpyrimidine?
The CAS number of 4-Chloro-5-fluoro-2-methylpyrimidine is 90772-35-3.
What is the molecular formula of 4-Chloro-5-fluoro-2-methylpyrimidine?
The molecular formula of 4-Chloro-5-fluoro-2-methylpyrimidine is C5H4ClFN2.
What is the molecular weight of 4-Chloro-5-fluoro-2-methylpyrimidine?
The molecular weight of 4-Chloro-5-fluoro-2-methylpyrimidine is 146.00 g/mol.
Where can I buy 4-Chloro-5-fluoro-2-methylpyrimidine?
You can request a quote for 4-Chloro-5-fluoro-2-methylpyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-5-fluoro-2-methylpyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-5-fluoro-2-methylpyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.