Combivir
TL;DR: Combivir (CAS 906479-25-2) is a chemical compound with molecular formula C10H16N5O13P3 and molecular weight 507.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Also Known As: Combivir, AZT triphosphate, Zidovudine triphosphate, AzTTP (aqueous solution), lamivudine, zidovudine drug combination
| Molecular Formula | C10H16N5O13P3 |
|---|---|
| Molecular Weight | 507.00 g/mol |
| LogP | 0.15472 |
| Topological Polar Surface Area | 272.67 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Exact Mass | 506.99576 |
| Heavy Atoms | 31 |
| Complexity | 1135.4734 |
Chemical Identifiers
| CAS Number | 906479-25-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-] |
Product Overview
Combivir (CAS 906479-25-2), with molecular formula C10H16N5O13P3 and molecular weight 507.00 g/mol. IUPAC: [[3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate.
Chemical Property Profile of Combivir
Property Insights of Combivir
The XLogP value of 0.15472 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Combivir. The TPSA of 272.67 Ų indicates high polarity, suggesting Combivir may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Combivir has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Combivir?
The CAS number of Combivir is 906479-25-2.
What is the molecular formula of Combivir?
The molecular formula of Combivir is C10H16N5O13P3.
What is the molecular weight of Combivir?
The molecular weight of Combivir is 507.00 g/mol.
Where can I buy Combivir?
You can request a quote for Combivir directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Combivir?
Yes, KEHONG BIO provides custom synthesis services for Combivir and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.