2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide
TL;DR: 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide (CAS 90357-52-1) is a chemical compound with molecular formula C11H9F3N2O3 and molecular weight 274.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop-2-enamide
Also Known As: 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop-2-enamide, 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-2-propenamide
| Molecular Formula | C11H9F3N2O3 |
|---|---|
| Molecular Weight | 274.06 g/mol |
| LogP | 3.1282 |
| Topological Polar Surface Area | 72.24 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 274.05652 |
| Heavy Atoms | 19 |
| Complexity | 552.6067 |
Chemical Identifiers
| CAS Number | 90357-52-1 |
|---|---|
| SMILES | CC(=C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F |
Product Overview
2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide (CAS 90357-52-1), with molecular formula C11H9F3N2O3 and molecular weight 274.06 g/mol. IUPAC: 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop-2-enamide.
Chemical Property Profile of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide
Property Insights of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide
The XLogP value of 3.1282 indicates that 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.24 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide. Following Lipinski's Rule of Five, 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide?
The CAS number of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide is 90357-52-1.
What is the molecular formula of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide?
The molecular formula of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide is C11H9F3N2O3.
What is the molecular weight of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide?
The molecular weight of 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide is 274.06 g/mol.
Where can I buy 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide?
You can request a quote for 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide?
Yes, KEHONG BIO provides custom synthesis services for 2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.